Wednesday's game that pits the Cleveland Guardians (21-27) versus the Chicago White Sox (20-30) at Progressive Field has a good chance to be a tight matchup based on our computer prediction, which projects a final score of 5-3 in favor of the Guardians. First pitch is at 1:10 PM ET on May 24.

The Guardians will give the ball to Cal Quantrill (2-2, 4.06 ERA), who is eyeing win No. 3 on the season, and the White Sox will turn to Michael Kopech (2-4, 4.83 ERA).

White Sox vs. Guardians Game Info & Odds

  • When: Wednesday, May 24, 2023 at 1:10 PM ET
  • Where: Progressive Field in Cleveland, Ohio
  • How to Watch on TV: BSGL
  • Live Stream: Watch this game on Fubo!

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White Sox vs. Guardians Score Prediction

Our pick for this game is Guardians 5, White Sox 4.

Total Prediction for White Sox vs. Guardians

  • Total Prediction: Over 7.5 runs

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Discover More About This Game

White Sox Performance Insights

  • The White Sox have played as the underdog in four of their past 10 games and have gone 2-2 in those contests.
  • In its previous 10 games with a total, Chicago and its opponents have combined to exceed the over/under just once.
  • The White Sox's previous 10 matchups have not had a spread posted by sportsbooks.
  • The White Sox have been chosen as underdogs in 30 games this year and have walked away with the win eight times (26.7%) in those games.
  • This year, Chicago has won three of 17 games when listed as at least +115 or worse on the moneyline.
  • Bookmakers have implied with the moneyline set for this matchup that the White Sox have a 46.5% chance of pulling out a win.
  • Averaging 4.1 runs per game (207 total), Chicago is the 20th-highest scoring team in baseball.
  • The White Sox have the 26th-ranked ERA (4.91) in the majors this season.

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White Sox Schedule

Date Opponent Score Pitching Matchup
May 19 Royals W 2-0 Michael Kopech vs Zack Greinke
May 20 Royals W 5-1 Lucas Giolito vs Jordan Lyles
May 21 Royals W 5-2 Lance Lynn vs Carlos Hernandez
May 22 @ Guardians L 3-0 Jimmy Lambert vs Hunter Gaddis
May 23 @ Guardians W 4-2 Dylan Cease vs Logan Allen
May 24 @ Guardians - Michael Kopech vs Cal Quantrill
May 25 @ Tigers - Lucas Giolito vs Alex Faedo
May 26 @ Tigers - Lance Lynn vs Joey Wentz
May 27 @ Tigers - Jimmy Lambert vs Michael Lorenzen
May 28 @ Tigers - Dylan Cease vs Eduardo Rodríguez
May 29 Angels - Michael Kopech vs Jaime Barria